| HAEMATOLOGICA Last update: 12/09/2008
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Efficacy of a combination of human recombinant erythropoietin + 13-cis-retinoic acid and dihydroxylated vitamin D3 to improve moderate to severe anaemia in low/intermediate risk myelodysplastic syndromes. Br J Haematol. 2008 Nov 19. [Epub ahead of print] Our combined therapy, independent of rEPO dosage, achieved in patients with unfavourable response predictors, a rate of anaemia improvement comparable to the best obtained in lower risk patients by high-dose rEPO
Primary Myelofibrosis: Update on Definition, Pathogenesis, and
Treatment.
Annu
Rev Med.
2008 Oct 23. [Epub ahead of print] An updated review of the
pathogenesis, definition, and treatment of PMF in light of the discovery
of JAK2 and MPL mutations, as well as other recent work in the
myeloproliferative neoplasm field. Expected final online publication date
for the Annual Review of Medicine Volume 60 is January 07, 2009. Please
see http://www.annualreviews.org/catalog/pubdates.aspx for revised
estimates.
Novel medical treatment modalities in hematology]Ugeskr Laeger. 2008 Jun 9;170(24):2115-9. Review. Danish. Hematologic response to hydroxyurea therapy in children with beta-thalassemia major.Georgian Med News. 2008 Mar;(156):91-4. Long-term HU therapy may correct the anemia and can eliminate or minimize the transfusional needs in children with beta+-thalassemia major in cases, when the patient's baseline HbF level is >/=15% and its increase during the treatment is up to 20%. New insights and therapeutics for immune-mediated thrombocytopenia. Response to hydroxyurea therapy in beta-thalassemia.
Am J Hematol. 2008 Jan 7;
[Epub ahead of print] Although a relatively
small number of previous studies suggest a modest response to
hydroxyurea (HU) therapy in beta-thalassemia, more recent investigations
have revealed that some transfusion-dependent patients can become
transfusion-independent following HU therapy.
Supportive care, growth factors, and new therapies in myelodysplastic syndromes.
Blood
Rev. 2007 Dec 6;
[Epub ahead of print] Review |