Old Archive of BMR
 

JOURNALS WITH ON LINE ARTICLES

 
Haematopoietic growth factors: current status   

Non transfusional haemostatic agents in the management of bleeding disorders 

Minimal blood utilization in surgery   

Blood salvage techniques to avoid homologous blood transfusion in orthopaedic surgery   

Rationale for the development of red-cell substitutes and status of the research

 

 
 

This journal covers artificial cells, blood substitutes, and immobilization biotechnology including gene therapy, cell therapy, enzyme therapy, bioencapsulation, microencapsulation, nanocapsules, nanoparticles, artificial organs, biomaterials, hybrid artificial organs, drug delivery systems, hemoperfusion

 

REVIEWS AND SURVEYS

Results from the Perfusion.com Cardiac Surgery Hematocrit Trend Survey: Observations and Evidence-Based Recommendations

Recombinant activated factor VIIa and hemostasis in critical care: a focus on trauma  Crit Care. 2005;9 Suppl 5:S37-42

 

VERY IMPORTANT FULL TEXT

Risks, benefits, alternatives and indications of allogenic blood transfusions.
Minerva Anestesiol. 2006 May;72(5):283-98. Review.

Live donor liver transplantation without blood products: strategies developed for Jehovah's Witnesses offer broad application.
Ann Surg. 2004 Aug;240(2):350-7.

Eliminating Blood Transfusions: New Aspects and Perspectives. Anesthesiology. 2000 Jul;93(1):242-255.

Recent developments: Blood transfusion medicine.
BMJ. 2002 Jul 20;325(7356):143-7. Review

Clinical review -Autologous transfusion.  BMJ 2002 (30 March);324:772-5  

Critical oxygen delivery in conscious humans is less than 7.3 ml O2 x kg(-1) x min(-1).
Anesthesiology. 2000 Feb;92(2):407-13.

Acute severe hemodilution to a hemoglobin of 1.3 g/dl tolerated in the presence of mild hypothermia.
Anesthesiology. 1999 Jun;90(6):1798-9.

Immunomodulatory aspects of transfusion: a once and future risk?
Anesthesiology. 1999 Sep;91(3):861-5. Review.

Impact of Alloantigens and Storage-associated Factors on Stimulated Cytokine Response in an In Vitro Model of Blood Transfusion. Anesthesiology. 2002 Nov;97(5):1102-9.

 


Anesthesiology
Blood salvage 
Blood substitutes 
Cardiac surgery 
Coagulants
Erythropoietin
General surgery 
Gynecologic surgery 
Head and neck surgery 
Hematological diseases
Hypervolemic hemodilution
Hypothermia
Hypotensive anesthesia
Hyperbaric Oxygen Therapy
Interventional radiology
Laparoscopic surgery
Neurosurgery 
Normovolemic hemodilution
Oncology
Orthopedic surgery
Preterm infant 
Thermal injury
Thoracic surgery
Thrombopoietin 
Transfusion issues 
Transfusion strategies 
Transplants
Trauma
Urologic surgery 
Vascular surgery
Other

 

Anesthesiology

 

Management of life-threatening epistaxis in a Jehovah's Witness.
Int J Clin Pract. 2003 Jan-Feb;57(1):60-1.

Severe anemia after gastrointestinal hemorrhage in a Jehovah's Witness: new treatment strategies.
Crit Care Med. 2002 Aug;30(8):1893-5.

Hyperoxia in extreme hemodilution.
Eur Surg Res. 2002 Jan-Apr;34(1-2):181-7. Review.

[Severity of anemia and operative morbidity and mortality. Report on 3 clinical cases in Jehovah's Witnesses and review of the literature]
Chir Ital. 2002 Jan-Feb;54(1):41-50. Italian.

Successful surgical treatment of a ruptured abdominal aortic aneurysm without homologous blood transfusion in a Jehovah's Witness: report of a case.
Surg Today. 2001;31(10):912-4.

Anaemia in the critically ill--the optimal haematocrit.
Ann Acad Med Singapore. 2001 May;30(3):293-9. Review.

Treating severe anemia in a trauma patient who is a Jehovah's witness.
Crit Care Nurse. 2001 Apr;21(2):69-72, 75-8, 80-2. Review. No abstract available.

The use of hyperbaric oxygen in the management of sever anaemia in a Jehovah's Witness.
Anaesthesia. 2000 Mar;55(3):293-4. No abstract available.

Extreme Intraoperative Blood Loss and Hemodilution in a Jehovah’s Witness: New Aspects in Postoperative Management
Anesthesiology 1999 December;91(6):1949-1951

Hyperbaric oxygen therapy in the management of severe acute anaemia in a Jehovah's witness.
Anaesthesia 1999 Sep;54(9):891-5 

Perioperative care of a Jehovah's Witness with a leaking abdominal aortic aneurism
British Journal of Anaesthesia 1998, 81:256-259

[Survival of very severe hemorrhage-induced anemia in a Jehovah's Witness]
Anasthesiol Intensivmed Notfallmed Schmerzther. 1996 Oct;31(8):501-4. German. No abstract available.

Management of severe blood loss after tumor resection in a Jehovah's Witness.
Gynakol Geburtshilfliche Rundsch. 1995;35(1):34-7.

Management of a multiply injured Jehovah's witness with severe acute anemia.
Orthop Rev. 1994 May;23(5):375. No abstract available.

Are transfusions overrated? Surgical outcome of Jehovah's Witnesses.
Am J Med. 1993 Feb;94(2):117-9.

Severe acute anaemia in a Jehovah's Witness. Survival without blood transfusion.
Anaesthesia. 1987 Jan;42(1):44-8.

Postoperative management of a severely anemic Jehovah's Witness.
Crit Care Med. 1983 Feb;11(2):142-3.

 



Blood salvage

 

Bacterial reduction by cell salvage washing and leukocyte depletion filtration.
Anesthesiology. 2003 Sep;99(3):652-5.

Intraoperative autologous blood transfusion for hemoperitoneum resulting from ectopic pregnancy or ovarian bleeding during laparoscopic surgery.
JSLS. 2003 Apr-Jun;7(2):97-100.

Rapid sequence quadruple joint replacement in a rheumatoid Jehovah's Witness.
Arch Orthop Trauma Surg. 2003 Apr;123(2-3):128-31. Epub 2003 Mar 27.

Perioperative blood salvage as an alternative to predonating blood for primary total knee and hip arthroplasty.
J Arthroplasty. 2002 Dec;17(8):1079-80

Perioperative blood management practices in elective orthopaedic surgery.
J Am Acad Orthop Surg. 2002 Nov-Dec;10(6):393-400. Review.

Intraoperative blood salvage in cancer surgery: safe and effective?
Transfus Apheresis Sci. 2002 Oct;27(2):153-7. Review.

Blood salvage with a continuous autotransfusion system compared with a haemofiltration system.
Perfusion. 2002 Sep;17(5):357-62.

Intraoperative blood salvage: a mathematical perspective.
Transfusion. 2002 Apr;42(4):451-5.

Study of five cell salvage machines in coronary artery surgery.
Transfus Med. 2002 Jun;12(3):173-9

Intraoperative blood salvage and autotransfusion in the management of ruptured ectopic pregnancy: a review.
East Afr Med J. 2001 Sep;78(9):465-7. Review.

Intra-operative blood salvage in abdominal trauma: a review of 5 years' experience.
Anaesthesia. 2001 Mar;56(3):217-20. Erratum in: Anaesthesia 2001 Aug;56(8):821.

Does cell-saver blood administration and free hemoglobin load cause renal dysfunction?
Am Surg. 2001 Jan;67(1):44-7.

Amniotic Fluid Removal during Cell Salvage in the Cesarean Section Patient
Anesthesiology 2000;92:1519-1522

Cell salvage in the Jehovah's Witness patient.
Anesth Analg. 2000 Jan;90(1):229-30. No abstract available.  

The results of intraoperative autotransfusion in orthopaedic surgery.
Bull Hosp Jt Dis. 1999;58(4):184-7

Clearance of fetal products and subsequent immunoreactivity of blood salvaged at cesarean delivery
Obstet Gynecol. 1999 Jun;93(6):968-72.

Blood irradiation for intraoperative autotransfusion in cancer surgery: demonstration of efficient elimination of
contaminating tumor cells. 
Transfusion. 1999 Jun;39(6):608-15. 

Vascular surgical society of great britain and ireland: autologous transfusion reduces blood transfusion requirements in aortic surgeryBr J Surg. 1999 May;86(5):698. 

Practicability and safety of intra-operative autotransfusion with irradiated blood. 
Anaesthesia. 1998 May;53 Suppl 2:42-3. No abstract available.

Effectiveness of leukocyte filters in reducing tumor cell contamination after intraoperative blood salvage in lung cancer patients
Vox Sang. 1997;72(4):221-4. 

Management of Jehovah's Witness patients for scoliosis surgery: the use of platelet and plasmapheresis. 
J Clin Anesth. 1997 Sep;9(6):510-3.

Laparoscopic examination of the traumatized spleen with blood salvage for autotransfusion. 
Am Surg. 1997 Jun;63(6):478-80.

Assessment of the availability of intraoperative autotransfusion in urological operations.
J Urol. 1997 May;157(5):1777-80.

Intraoperative autologous blood transfusion in intracranial surgery. 
Neurosurgery. 1997 Apr;40(4):765-71; discussion 771-2

The influence of acute preoperative plasmapheresis on coagulation tests, fibrinolysis, blood loss and transfusion requirements in cardiac surgery
Eur J Cardiothorac Surg. 1997 Mar;11(3):557-63

Advantages and limitations of intraoperative mechanical autotransfusion in al prostatectomies
Anaesthesist. 1997 Feb;46(2):101-7.

Intraoperative blood salvage in abdominal uterine myomectomy
Int J Gynaecol Obstet. 1997 Feb;56(2):141-5

Autotransfusion utilization in abdominal trauma
Am Surg. 1997 Jan;63(1):47-9. 

Plateletpheresis before redo CABG diminishes excessive blood transfusion. 
Ann Thorac Surg. 1996 Nov;62(5):1373-8; discussion 1378-9. 

Intraoperative salvage in patients undergoing elective abdominal aortic aneurysm repair: an analysis of cost and benefit.
J Vasc Surg. 1996 Aug;24(2):213-8

Intraoperative autotransfusion in aortic surgery: comparison of whole blood autotransfusion versus cell separation. 
J Vasc Surg. 1996 Jul;24(1):102-8

Intraoperative autologous blood collection and autotransfusion in the surgical management of early cancers of the uterine cervix
Obstet Gynecol. 1995 Sep;86(3):373-8

Intraoperative autologous transfusion in emergency surgery for spine trauma
J Trauma. 1994 May;36(5):639-43

Extracorporeal circulation as a blood conservation technique for extensive pelvic operations
J Am Coll Surg. 1994 Apr;178(4):397-400. 

 



Blood substitutes 

 

Diaspirin-crosslinked hemoglobin reduces blood transfusion in noncardiac surgery: a multicenter, randomized, controlled, double-blinded trial.
Anesth Analg. 2003 Aug;97(2):323-32, table of contents.

The use of haemoglobin glutamer-250 (HBOC-201) as an oxygen bridge in patients with acute anaemia associated with surgical blood loss.
Expert Opin Biol Ther. 2003 Jun;3(3):509-17.

Safety and preliminary efficacy of hemoglobin raffimer for patients undergoing coronary artery bypass surgery.
J Cardiothorac Vasc Anesth. 2002 Dec;16(6):695-702.

Use of perflubron emulsion to decrease allogeneic blood transfusion in high-blood-loss non-cardiac surgery: results of a European phase 3 study.
Anesthesiology. 2002 Dec;97(6):1338-49.

Polymerized human Hb use in acute chest syndrome: a case report.
Transfusion. 2002 Nov;42(11):1422-7.

The life-sustaining capacity of human polymerized hemoglobin when red cells might be unavailable.
J Am Coll Surg. 2002 Oct;195(4):445-52; discussion 452-5.

New approach to management of life-threatening bleeding in a Jehovah's Witness.
Crit Care Med. 2002 Aug;30(8):1930-1. No abstract available.

Severe anemia after gastrointestinal hemorrhage in a Jehovah's Witness: new treatment strategies.
Crit Care Med. 2002 Aug;30(8):1893-5.

Blood substitute and erythropoietin therapy in a severely injured Jehovah's witness.
N Engl J Med. 2002 Apr 4;346(14):1097-8. No abstract available.

The use of bovine hemoglobin glutamer-250 (Hemopure) in surgical patients: results of a multicenter, randomized, single-blinded trial.
Anesth Analg. 2002 Apr;94(4):799-808, table of contents.

Blood substitutes in surgery.
Surgery. 2000 Jun;127(6):599-602

Transfusions of polymerized bovine hemoglobin in a patient with severe autoimmune hemolytic anemia.
N Engl J Med. 2000 Jun 1;342(22):1638-43. No abstract available.

The reduction of the allogenic transfusion requirement in aortic surgery with a hemoglobin-based solution.
J Vasc Surg. 2000 Feb;31(2):299-308.

Perflubron emulsion delays blood transfusions in orthopedic surgery. European Perflubron Emulsion Study Group. 
Anesthesiology 1999 Nov;91(5):1195-208 

The value of oxygen-carrying solutions in the operative setting, as determined by mathematical modeling. 
Transfusion. 1999 Apr;39(4):396-402.

                                                                                                                                                          




Cardiac surgery

 

Blood conservation strategies in Jehovah's Witness patients undergoing complex aortic surgery: A report of three cases.
J Cardiothorac Vasc Anesth. 2003 Aug;17(4):528-35. No abstract available.

Treatment of excessive bleeding in Jehovah's Witness patients after cardiac surgery with recombinant factor VIIa (NovoSeven).
Anesthesiology. 2003 Jun;98(6):1513-5. No abstract available.

Repair of hypoplastic left heart syndrome of a 4.25-kg Jehovah's witness.
Perfusion. 2002 May;17(3):221-5.

Epoetin alpha in elective coronary and valve surgery in Jehovah's Witnesses patients. Experience in 45 patients.
Minerva Cardioangiol. 2002 Apr;50(2):125-31. English, Italian.

Low-prime perfusion circuit and autologous priming in CABG surgery on a Jehovah's Witness: a case report.
Perfusion. 2002 Jan;17(1):69-72.

Use of desmopressin and erythropoietin in an anaemic Jehovah's Witness patient with severely impaired coagulation capacity undergoing stentless aortic valve replacement.
Perfusion. 2001 Nov;16(6):485-9.

Redo cardiac surgery in a Jehovah's Witness, the importance of a multidisciplinary approach to blood conservation.
Perfusion. 2000 Jun;15(3):251-5. 

Pharmacological strategies to decrease excessive blood loss in cardiac surgery: a meta-analysis of clinically relevant endpoints.
Lancet. 1999 Dec 4;354(9194):1940-7.

Cardiac surgery in adults and children without use of blood. 
Ann Thorac Cardiovasc Surg. 1998 Feb;4(1):3-11

Open heart operations without transfusion using a multimodality blood conservation strategy in 50 Jehovah's Witness patients: implications for a "bloodless" surgical technique. 
J Am Coll Surg. 1997 Jun;184(6):618-29.

Coronary stent placement as a bridge to coronary artery bypass surgery in an unstable, anemic Jehovah's Witness patient: a case report and review of bloodless surgery techniques.
Conn Med. 1997 Apr;61(4):195-9. Review.

High risk cardiac surgery in Jehovah's Witnesses. 
J Cardiovasc Surg (Torino). 1996 Oct;37(5):511-5

Open-heart surgery in Jehovah's Witness patients.
Cardiovasc Surg. 1996 Jun;4(3):311-4.

Bloodless open-heart surgery in infants and children. 
Perfusion. 1994;9(4):257-63. 

Transfusion guidelines for cardiovascular surgery: lessons learned from operations in Jehovah's Witnesses.
J Vasc Surg. 1992 Dec;16(6):825-9; discussion 829-31.

Reoperation, emergency and urgent open cardiac surgery in Jehovah's Witnesses.
Chest. 1992 Jul;102(1):50-3.

Risk factors for cardiac operations in adult Jehovah's Witnesses.
Ann Thorac Surg. 1991 Mar;51(3):448-50.

Cardiovascular surgery in Jehovah's Witnesses. Report of 542 operations without blood transfusion.
JAMA. 1977 Sep 19;238(12):1256-8.

                                                                                                                                                         



Coagulants 

Pharmacological strategies to decrease excessive blood loss in cardiac surgery: a meta-analysis of clinically relevant endpoints.
Lancet. 1999 Dec 4;354(9194):1940-7.
Recombinant Factor VIIa Is Effective for Bleeding and Surgery in Patients With Glanzmann Thrombasthenia
Blood. 1999 Dec 1;94(11):3951-3953
Treatment of traumatic bleeding with recombinant factor VIIa.                                                                                                                           Lancet 1999  Nov 27;354(9193):1879
Reducing perioperative blood loss in patients undergoing total hip arthroplasty
Int J Artif Organs. 1999 Jan;22(1):47-51.
Aprotinin efficacy on intraoperative bleeding and transfusion requirements in orthotopic liver transplantation
Transfusion. 1994 Jun;34(6):507-11. 
Aprotinin therapy to reduce blood loss in Jehovah's Witnesses.
Can J Anaesth. 1994 Jan;41(1):77-8. No abstract available.
Recombinant factor VIIa for intracranial haemorrhage in a Jehovah's Witness with severe haemophilia A and factor VIII inhibitors. 
Blood Coagul Fibrinolysis. 1993 Dec;4(6):1031-3.



Erythropoietin

Cost-effectiveness of epoetin and autologous blood donation in reducing allogeneic blood transfusions in coronary artery bypass graft surgery
Transfusion 2000 40: 673-681                                                                                                                                     Recombinant human erythropoietin improves health-related quality of life in patients with rheumatoid arthritis and anaemia of chronic disease; utility measures correlate strongly with disease activity measures. 
Rheumatol Int. 1999;18(5-6):201-6. 
Optimizing erythropoietin therapy. 
Curr Opin Hematol. 1999 May;6(3):121-6. 
Recombinant human erythropoietin treatment of postpartum anemia. Preliminary results. 
Eur J Obstet Gynecol Reprod Biol. 1998 Oct;81(1):27-31. 
Erythropoietin therapy. 
N Engl J Med. 1997 Mar 27;336(13):933-8. Review. No abstract available
Erythropoietin permits high-dose chemotherapy with peripheral blood stem-cell transplant for a Jehovah's Witness. 
Am J Hematol. 1997 May;55(1):51-2. No abstract available.
Recombinant erythropoietin for the treatment of anemia in inflammatory bowel disease.
N Engl J Med 1996 Mar 7;334(10):619-23 
Erythropoetin accelerates hematocrit recovery in post-surgical anemia
Am Surg. 1995 Jan;61(1):74-7. 



General surgery

Major hepatic resection without blood transfusion: experience with total vascular exclusion
J Gastroenterol Hepatol 1999 May;14 Suppl:S28-31 
Extended hemipelvectomy in a Jehovah's Witness with erythropoietin support. 
Am Surg. 1998 Nov;64(11):1074-6.
Elective splenectomy in an anemic Jehovah's Witness patient with cirrhosis. 
Anesth Analg. 1998 Sep;87(3):529-30. No abstract available.
Pancreaticoduodenectomy without homologous blood transfusion in an anemic Jehovah's Witness. 
Arch Surg. 1992 Mar;127(3):349-51. 
Elective surgery without transfusion: influence of preoperative hemoglobin level and blood loss on mortality. 
Am J Surg. 1990 Mar;159(3):320-4. 



Gynecologic surgery 

Uterine Artery Embolization for Fibroids: Considerations in Patient Selection and Clinical Follow-up
Medscape Women's Health 4(5), 1999
Pelvic arterial embolization for control of obstetric hemorrhage: A five-year experience. 
Am J Obstet Gynecol. 1999 Jun;180(6 Pt 1):1454-1460.
Bloodless surgery: Establishment of a program for the special medical needs of the Jehovah's Witness community-The gynecologic surgery experience at a community hospital
Am J Obstet Gynecol. 1999 Jun;180(6 Pt 1):1491-1498
Pregnancy in a Jehovah's witness with cervical cancer and anemia
Gynecol Oncol. 1998 Nov;71(2):330-2. 



Head and neck surgery

Management of Jehovah's Witness patients undergoing major head and neck surgery. 
Head Neck. 1999 Jan;21(1):80-4. 
Head and neck surgery in the Jehovah's Witness patient. 
Otolaryngol Head Neck Surg. 1996 Apr;114(4):669-72. No abstract available.
Craniomaxillofacial surgery in the Jehovah's Witness patient. 
Plast Reconstr Surg. 1994 May;93(6):1258-63. 



Hematological diseases 

Hematopoietic stem cell allografts using a non-myeloablative conditioning regimen can be safely performed on an outpatient basis: report of four cases.
Bone Marrow Transplant. 2000 Jan;25(2):131-3.                                                                                                                                                   Successful treatment for acute lymphoblastic leukemia without blood transfusion in a Jehovah's Witness. 

Am J Hematol. 1999 Feb;60(2):168-9. No abstract available.
Acute leukaemia in Jehovah's Witnesses. 
Br J Haematol. 1998 Mar;100(4):664-8.
Successful treatment of acute promyelocytic leukemia using all-trans retinoic acid and erythropoietin in a Jehovah's Witness boy. 
Ann Hematol. 1998 Jan;76(1):43-4.
Clinical and ethical issues in the treatment of a Jehovah's Witness with acute myeloblastic leukemia
Arch Intern Med. 1997 Aug 11-25;157(15):1753-7. Review
Successful treatment of a Jehovah's Witness with acute promyelocytic leukemia
Int J Hematol. 1997 Jun;65(4):415-6. No abstract available.
Successful treatment of acute promyelocytic leukemia in a pregnant Jehovah's Witness with all-trans retinoic acid, rhG-CSF, and erythropoietin. 
Am J Hematol. 1996 Mar;51(3):251-2. No abstract available.
Use of 2-chlorodeoxyadenosine, granulocyte-colony-stimulating factor, and erythropoietin in a Jehovah's Witness with hairy cell leukemia
Am J Hematol. 1995 Jul;49(3):255-6. No abstract available
When to transfuse blood in sickle cell disease? Lessons from Jehovah's Witnesses. 
Ann Clin Lab Sci. 1994 Sep-Oct;24(5):396-400.
Long-term continuous complete remission of acute myeloid leukemia in a Jehovah's witness treated without blood support. 
Haematologica. 1994 Mar-Apr;79(2):180-1. 



Hypervolemic hemodilution 

 

Acute hypervolaemic haemodilution to avoid blood transfusion during major surgery.
Lancet. 1990 Nov 24;336(8726):1295-7.

Hypervolaemic haemodilution in an anaemic Jehovah's Witness. 
Br J Anaesth. 1990 May;64(5):646-8. 




Hypothermia 

Acute severe hemodilution to a hemoglobin of 1.3 g/dl tolerated in the presence of mild hypothermia. 
Anesthesiology 1999 Jun;90(6):1798-9 



Hypotensive anesthesia

 

Recent advances in obstetric anesthesia.
J Anesth. 2003;17(1):30-41.

Preoperative Acute Normovolaemic Hemodilution (ANH) in combination with Hypotensive Epidural Anaesthesia (HEA) during knee arthroplasty surgery. No effect on transfusion rate. A randomized controlled trial [ISRCTN87597684].
BMC Anesthesiol. 2002 Apr 18;2(1):1.

Eliminating blood transfusions: don't forget hypotensive anesthesia.
Anesthesiology. 2002 Jan;96(1):252-3. No abstract available.

Hypotensive epidural anesthesia in total knee replacement without tourniquet: reduced blood loss and transfusion.
Reg Anesth Pain Med. 2001 Mar-Apr;26(2):105-10.

Perioperative management for total en bloc spondylectomy--the effects of preoperative embolization and hypotensive anesthesia.
Masui. 2000 Feb;49(2):168-71. Japanese   

Clinical application of a blood pressure autoregulation system during hypotensive anesthesia.
World J Surg. 1999 Dec;23(12):1258-63. 

Randomized trial of hypotensive epidural anesthesia in older adults.
Anesthesiology. 1999 Oct;91(4):926-35.   

Deliberate hypotensive epidural anesthesia for patients with normal and low cardiac output.
Anesth Analg. 1994 Nov;79(5):899-904.

Hypotensive anesthesia for scoliosis surgery in Jehovah's Witnesses. 
Spine. 1991 Mar;16(3):304-6. 

                                                                                                                                                             



Hyperbaric oxygen therapy

 

Hyperbaric oxygen reverses organ dysfunction in severe anemia.
Anesthesiology. 2000 Oct;93(4):1149-52. No abstract available.

The use of hyperbaric oxygen in the management of severe anaemia in a Jehovah's Witness.
Anaesthesia. 2000 Mar;55(3):293-4. No abstract available

Hyperbaric oxygen therapy in the management of severe acute anaemia in a Jehovah's witness.
Anaesthesia 1999 Sep;54(9):891-5    

                                                                                              



Interventional radiology

Uterine Artery Embolization for Fibroids: Considerations in Patient Selection and Clinical Follow-up
Medscape Women's Health 4(5), 1999
Secondary Postpartum Hemorrhage: Treatment with Selective Arterial Embolization
Radiology. 1999;212:385-389.
Pelvic arterial embolization for control of obstetric hemorrhage: A five-year experience. 
Am J Obstet Gynecol. 1999 Jun;180(6 Pt 1):1454-1460. 
Acute hemorrhage in chronic pancreatitis: diagnosis and treatment options including superselective microcoil embolization. 
Pancreas. 1999 May;18(4):399-402.
Uterine artery embolization--a successful treatment to control bleeding cervical pregnancy with a simultaneous intrauterine gestation. 
Hum Reprod. 1999 Feb;14(2):553-5. 
Life-threatening primary postpartum hemorrhage: treatment with emergency selective arterial embolization. 
Radiology. 1998 Aug;208(2):359-62
Selective arterial embolization for the control of lower gastrointestinal bleeding.
Am J Surg. 1997 Jul;174(1):24-8. 



Laparoscopic surgery 

Laparoscopic vs Open  Splenectomy 
Arch Surg. 1999;134:1263-1269
Laparoscopic splenectomy in a Jehovah's Witness with profound anemia. 
Surg Endosc. 1997 Aug;11(8):850-1.
Autotransfusion with laparoscopically salvaged blood in trauma: report on 21 cases. 
Surg Laparosc Endosc. 1996 Feb;6(1):46-8. 



Neurosurgery

Evaluation of acute normovolemic hemodilution for surgical repair of craniosynostosis.
J Neurosurg Anesthesiol. 2000 Jan;12(1):33-6.
Erythropoietin-augmented isovolemic hemodilution in skull-base surgery. Case report. 
J Neurosurg. 1994 Apr;80(4):740-4. 
Use of recombinant human erythropoietin to avoid blood transfusion in a Jehovah's Witness requiring hemispherectomy.  Case report. 
J Neurosurg. 1993 Oct;79(4):600-2. 



Normovolemic hemodilution 

Evaluation of acute normovolemic hemodilution for surgical repair of craniosynostosis.
J Neurosurg Anesthesiol. 2000 Jan;12(1):33-6.
Hemodilution as a method to reduce transfusion requirements in adolescent spine fusion surgery
Spine. 1999 Feb 1;24(3):219-22; discussion 223-4.
Acute normovolemic hemodilution. 
Clin Orthop. 1998 Dec;(357):74-81. Review. 
Acute normovolemic hemodilution should replace the preoperative donation of autologous blood as 
a method of autologous-blood procurement. 
Transfusion. 1998 May;38(5):473-6. Review. No abstract available.



Oncology

Recombinant human erythropoietin in the treatment of cancer-related or chemotherapy-induced anaemia in patients with solid tumours
Med Oncol. 1998 Aug;15 Suppl 1:S19-28. Review.
Management of chemotherapy-induced anemia in solid tumors
Semin Oncol. 1998 Jun;25(3 Suppl 7):23-6. Review. 
The effect of GM-CSF on reticulocytes, haemoglobin and haematocrit in patients receiving chemotherapy for solid tumours.
Clin Lab Haematol. 1996 Mar;18(1):7-12. 



Orthopedic surgery 

A comparative study of the postoperative allogeneic blood-sparing effect of tranexamic acid versus acute normovolemic hemodilution after total knee replacement.
Anesth Analg. 1999 Dec;89(6):1382-7
Technologies to minimize blood transfusion in cardiac and orthopedic surgery. Results of a practice variation survey in nine countries. International Study of Peri-operative Transfusion (ISPOT) Investigators.
Int J Technol Assess Health Care. 1999 Fall;15(4):717-28
The use of fibrin tissue adhesive to reduce blood loss and the need for blood transfusion after total knee arthroplasty. A prospective, randomized, multicenter study                                                                                                                                                                                              J Bone Joint Surg Am 1999 Nov;81(11):1580-8 
The use of erythropoietin in the management of Jehovah's Witnesses who have revision total hip arthroplasty
J Bone Joint Surg Am. 1996 Oct;78(10):1548-52.
Management of Jehovah's Witness patients for scoliosis surgery: the use of platelet and plasmapheresis. 
J Clin Anesth. 1997 Sep;9(6):510-3.
Conference Summaries from American Academy of Orthopaedic Surgeons 66th Annual Meeting 
February 4-8, 1999. Multicomponent Pheresis and Autologous Platelet Gel in Children and Adolescents Undergoing Spinal Surgery
© Medscape, Inc



Preterm infant

Avoidance of red blood cell transfusion in an extremely preterm infant given recombinant human erythropoietin therapy. 
J Paediatr Child Health. 1994 Aug;30(4):360-2. 
Erythropoietin in very preterm infants. 
 J Paediatr Child Health. 1994 Aug;30(4):356-9. 

 



Thermal injury

A conservative thermal injury treatment protocol for the appropriate Jehovah's Witness candidate. 
J Burn Care Rehabil. 1997 Mar-Apr;18(2):133-8.
Anesthesia and intensive care management of severely burned children of Jehovah's Witnesses. 
Anaesthesist. 1996 Feb;45(2):171-5. German
Preventing blood transfusion in a severely burned Jehovah's witness. 
Chirurg. 1994 Nov;65(11):1066-8. German. 
The use of recombinant human erythropoietin and cultured epithelial autografts in a Jehovah's Witness with a major thermal injury. 
Burns. 1994 Apr;20(2):176-7. 
Successful use of recombinant human erythropoietin in a Jehovah's Witness with a thermal injury. 
J Burn Care Rehabil. 1994 Jan-Feb;15(1):42-5. 



Thoracic surgery

Lung transplantation in a Jehovah's Witness 
J Heart Lung Transplant 1999 Aug;18(8):796-800 
Successful reoperation for ascending aorta and arch aneurysm in a Jehovah's Witness. 
Ann Thorac Surg. 1994 Sep;58(3):871-3. 



Thrombopoietin

Thrombopoietin induces rapid resolution of thrombocytopenia after orthotopic liver transplantation
through increased platelet production
Blood 2000 95: 795-801
Risks, costs, and alternatives to platelet transfusions. 
Leuk Lymphoma. 1999 Jun;34(1-2):71-84. 
Physiology and clinical applications of platelet growth factors. 
Curr Opin Hematol. 1999 May;6(3):127-34
Recombinant human thrombopoietin in combination with granulocyte colony-stimulating factor enhances mobilization of  peripheral blood progenitor cells, increases peripheral blood platelet concentration, and accelerates hematopoietic recovery  following high-dose chemotherapy. 
Blood. 1999 May 1;93(9):2798-806. 
Thrombopoietic cytokines and reversal of thrombocytopenia after liver transplantation. 
Eur J Gastroenterol Hepatol. 1999 Feb;11(2):151-6. 
Thrombopoietin promotes hematopoietic recovery and survival after high-dose whole body irradiation. 
Int J Radiat Oncol Biol Phys. 1999 Mar 1;43(4):867-75. 



Transfusion issues

 Hepatitis-associated aplastic anemia and transfusion-transmitted virus infection.
Intern Med. 2000 Dec;39(12):1068-70.
Immunomodulatory Aspects of Transfusion: A Once and Future Risk?                                                                                                          Anesthesiology. 1999 Sep;91(3):861-5. Review                                                                                                        Transfusion-Associated Infections with Cytomegalovirus and Other Human Herpesviruses                                                                              Infusion Therapy and Transfusion Medicine 27:3:2000, 138-143.                                                                                                Fulminant Non–A-G Viral Hepatitis Leading to Liver Transplantation                                                                                                                       Arch Intern Med. 2000;160:388-392                                                                                                                              Prevalence of viral hepatitis C in patients with inflammatory bowel disease in the region of nice and evaluation of risk factors                                                                                                                                                                                                                   Gastroenterol Clin Biol 2000 Jan;24(1):77-81                                                                                                                   Patterns of and risk factors for recurrence after liver resection for well-differentiated hepatocellular carcinoma: a special reference to multicentric carcinogenesis after operation.                                                                                                                                Hepatogastroenterology. 1999 Nov-Dec;46(30):3212-5                                                                                                            
Hepatitis C virus transmission by a blood donation negative in nucleic acid amplification tests for viral                                                                                                                                 
Lancet 2000 Jan 1;355(9197):41-2  
Stored red blood cells selectively activate human neutrophils to release IL-8 and secretory PLA2.                                                              Shock. 2000  Jan;13(1):29-33.
Blood Transfusion First, Do No Harm
Chest 1999 Nov; 116:1149-1150
Impact of Blood Transfusions on Inflammatory Mediator Release in Patients Undergoing Cardiac Surgery 
Chest, 1999 Nov; 116:1233-1239
Prevalence of TT virus in patients with fulminant hepatic failure in Japan.
J Gastroenterol 1999 Oct;34(5):589-93 
The pathology of transfusion-related acute lung injury
Am J Clin Pathol. 1999 Aug;112(2):216-21. 
Serious hazards of transfusion (SHOT) initiative: analysis of the first two annual reports
BMJ 1999;319:16-19 ( 3 July )
Infections in Oncology:  Infectious Causes of Malignancy
Cancer Control; JMCC 6(3):294-300, 1999
Viral etiology of human cancer: a historical perspective
Haematologica 1999 ; 385-389 
Prognostic significance of perioperative blood transfusions in resectable thoracic esophageal cancer
Am J Gastroenterol. 1999 Mar;94(3):757-65. 
Hepatectomy for hepatocellular carcinoma: toward zero hospital deaths. 
Ann Surg. 1999 Mar;229(3):322-30. 
A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion Requirements in Critical Care Investigators, Canadian Critical Care Trials Group. 
N Engl J Med. 1999 Feb 11;340(6):409-17. 
Transfusions in Critically Ill Patients
N Engl J Med 1999, Feb 11;  340 (6) 
Prion diseases and blood transfusion 
Transfus Clin Biol. 1999 Feb;6(1):24-8. French. 
New-variant Creutzfeldt-Jakob disease: the risk of transmission by blood transfusion. 
Blood Rev. 1998 Dec;12(4):255-68. Review. 
Emergence of new viral infections: implications for the blood supply. 
Biologicals. 1998 Jun;26(2):77-84. Review. 
Adverse effect of perioperative blood transfusions on survival after hepatic resection for hepatocellular carcinoma.
Hepatogastroenterology. 1997 Sep-Oct;44(17):1390-6
Blood transfusion. An independent risk factor for postinjury multiple organ failure.
Arch Surg. 1997 Jun;132(6):620-4; discussion 624-5.
Transfusing red blood cells stored in citrate phosphate dextrose adenine-1 for 28 days fails to improve tissue oxygenation in rats. 
Crit Care Med. 1997 May;25(5):726-32.
Transfusion of red cells is associated with increased incidence of bacterial infection after colorectal surgery: a prospective  study. 
Transfusion. 1997 Feb;37(2):126-34.
Effect of stored-blood transfusion on oxygen delivery in patients with sepsis
JAMA. 1993 Jun 16;269(23):3024-9.



Transfusion strategies

Critical oxygen delivery in conscious humans is less than 7.3 ml O2 x kg(-1) x min(-1).
Anesthesiology. 2000 Feb;92(2):407-13.
Transfusion medicine. First of two parts--blood transfusion

N Engl J Med. 1999 Feb 11;340(6):438-47. Review. No abstract available.
Transfusion medicine. Second of two parts--blood conservation
N Engl J Med. 1999 Feb 18;340(7):525-33. Review. No abstract available.
Do we know when to transfuse red cells to treat acute anemia? 
Transfusion. 1998 Jun;38(6):517-21. Review. No abstract available.
Human cardiovascular and metabolic response to acute, severe isovolemic anemia
JAMA. 1998 Jan 21;279(3):217-21.
New transfusion strategies
Am J Surg. 1997 Jan;173(1):49-52. Review. 
Nursing strategies to minimize blood loss associated with phlebotomy
AACN Clin Issues. 1996 May;7(2):277-87. Review. 
Ten strategies to reduce blood loss in orthopedic surgery. 
Am J Surg. 1995 Dec;170(6A Suppl):64S-68S. 
Combined aprotinin and erythropoietin use for blood conservation: results with Jehovah's Witnesses. 
Ann Thorac Surg. 1994 Nov;58(5):1397-403. 
What can we learn about the need for transfusion from patients who refuse blood? The experience with Jehovah'sWitnesses. 
Transfusion. 1994 May;34(5):396-401. 
Are transfusions overrated? Surgical outcome of Jehovah's Witnesses. 
Am J Med. 1993 Feb;94(2):117-9. 
Management of the severely anemic patient who refuses transfusion: lessons learned during the care of a Jehovah's  Witness. 
Ann Intern Med. 1992 Dec 15;117(12):1042-8. Review. 



Transplants

 

Transfusion free surgery: single institution experience of 27 consecutive liver transplants in Jehovah's Witnesses.
J Am Coll Surg. 2005 Sep;201(3):412-7.

Liver transplantation in Jehovah's witnesses.
Transpl Int. 2005 Aug;18(8):929-36.

Right lobe living-related liver transplantation in a Jehovah's Witness.
Transpl Int. 2003 Aug 16 [Epub ahead of print] No abstract available.

Transfusion-free reduced-intensity conditioned allogeneic stem cell transplantation in a Jehovah's witness.
Bone Marrow Transplant. 2003 Aug;32(4):437-8.

Myeloablative therapy and bone marrow transplantation in Jehovah's Witnesses with malignancies: single center experience.
Bone Marrow Transplant. 2003 Aug;32(4):433-6

Simultaneous pancreas-kidney transplantation in Jehovah's Witness patients.
Clin Transplant. 2003 Apr;17(2):140-3.

Lung transplantation in a Jehovah's witness. Case report in a twinning procedure.
J Cardiovasc Surg (Torino). 2003 Feb;44(1):131-4.

Red cell aplasia due to erythrovirus parvovirus B19 infection in a Jehovah's witness with post-transplant EBV-induced aggressive lymphoma: management considerations.
Leuk Lymphoma. 2002 Jan;43(1):211-3.

Liver transplantation in a Jehovah's Witness with ankylosing spondylitis.
Can J Anaesth. 2000 Jul;47(7):642-6.

Successful autologous bone marrow transplant without the use of blood product support.
Bone Marrow Transplant. 2000 Jul;26(2):227-9.

Challenging issues associated with organ transplantation for Jehovah's Witness individuals.
J Heart Lung Transplant. 2000 Feb;19(2):119-20. No abstract available.

Lung transplantation in a Jehovah's Witness 
J Heart Lung Transplant 1999 Aug;18(8):796-800 

Liver transplantation in a Jehovah's witness. 
Lancet. 1999 May 15;353(9165):1680 No abstract available.

Erythropoietin permits high-dose chemotherapy with peripheral blood stem-cell transplant for a Jehovah's Witness. 
Am J Hematol. 1997 May;55(1):51-2. No abstract available.

Liver transplantation for fulminant hepatic failure in a Jehovah's Witness. 
Clin Transplant. 1996 Oct;10(5):404-7

Use of recombinant human erythropoietin to facilitate liver transplantation in a Jehovah's Witness. 
Br J Anaesth. 1996 May;76(5):740-3. 

Liver transplantation without the use of blood products. 
Arch Surg. 1994 May;129(5):528-32; discussion 532-3.

Heart transplantation in Jehovah's Witnesses. An initial experience and follow-up. 
Arch Surg. 1990 Nov;125(11):1430-3. 

A single-center experience of renal transplantation in thirteen Jehovah's Witnesses.
Transplantation. 1988 Jun;45(6):1045-9.

Heart transplantation in a Jehovah's Witness.
J Heart Transplant. 1986 Mar-Apr;5(2):175-7.



Trauma 

Nonoperative management of a splenic tear in a Jehovah's Witness with hemophilia. 
J Trauma. 1996 Feb;40(2):299-301. Review.
Traumatically injured Jehovah's Witnesses: a sixteen-year experience of treatment and transfusion dilemmas at a level I trauma center. 
J Trauma. 1995 Oct;39(4):681-5. 
Use of recombinant human erythropoietin (r-HuEPO) in a Jehovah's Witness refusing transfusion of blood products: case report. 
J Trauma. 1990 Nov;30(11):1406-8. 



Urologic surgery 

Acute normovolemic hemodilution can replace preoperative autologous blood donation as a standard of care for autologous blood procurement in radical prostatectomy. 
Anesth Analg. 1997 Nov;85(5):953-8.



Vascular surgery

 

Advances in general and vascular surgical care of Jehovah's Witnesses.
Int Surg. 2000 Jul-Sep;85(3):257-65.

Vascular surgical society of great britain and ireland: autologous transfusion reduces blood transfusion requirements in aortic surgery
Br J Surg. 1999 May;86(5):698. 

Perioperative care of a Jehovah's Witness with a leaking abdominal aortic aneurysm
Br J Anaesth. 1998 Aug;81(2):256-9. 

 



Other


Treatment of chronic bleeding from gastric antral vascular ectasia (GAVE) with estrogen-progesterone in
cirrhotic patients: an open pilot study.                                                                                                                                                                          Am J Gastroenterol 1999 Oct;94(10):2909-11

 
Other interesting readings

                                                                                                                                                                           bulletSerious hazards of transfusion (SHOT) initiative: analysis of the first two annual reports                                                            bulletImmunomodulatory Aspects of Transfusion: A Once and Future Risk?
bulletOncology Treatment Updates: Therapeutic Options for Anemia and Fatigue  
bulletBlood Transfusion First, Do No Harm! 
bulletBetter blood transfusion 
bulletTransfusions in critically ill patients
bulletCochrane Injuries Group Albumin Reviewers
bulletMinimally Invasive and Noninvasive Diagnosis and Therapy in Critically Ill and Injured Patients
bulletAcute lower intestinal  bleeding   Part I: Clinical presentation and  diagnosis
bulletThird Millennium Challenge: Hepatitis C
bullet"TT" virus  - We hope it's harmless...